Global Menopausal Hot Flashes Market to Expand at 3.70% CAGR from 2015 to 2023

Menopausal hot flashes are a form of flushing experiencing by menopausal or perimenopausal women due to falling levels of estradiol. Apart from the lack of estradiol, other hormonal imbalances caused by menopause also lead to hot flashes. Menopausal hot flashes typically manifest as half a minute to two minutes of feeling intense heat, with sweating and elevated heartbeat.

Menopausal hot flashes are reported by around 75% of women in the developed world, including North America and Western Europe. Usually, hot flashes reduce in intensity as well as frequency over a few years post-menopause, but they can also, occasionally, extend into old age. Similarly, the intensity of menopausal hot flashes varies, with various women reporting different levels of discomfiture while experiencing menopausal hot flashes.

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The global menopausal hot flashes market therapeutics was worth close to US$3.8 bn in 2014, according to leading market intelligence company Transparency Market Research. Exhibiting a CAGR of 3.70% from 2015 to 2023, the market is expected to rise to a valuation of US$5.3 bn.

Non-hormonal Therapy to Rise in Demand in Menopausal Hot Flashes Market

At present, the global menopausal hot flashes market is led by the segment of hormonal therapy. Due to its older establishment in the healthcare industry and consistent success in alleviating hot flashes, as well as the integral role of hormones in the etiology of menopausal hot flashes, hormone therapy has remained the dominant treatment type in the menopausal hot flashes market.

Among hormonal therapy, estrogen and progesterone are the key hormones, with estrogen accounting for an overwhelmingly dominant share of the market due to its practically unchallenged position as the most efficacious treatment type. Premarin was the most sold estrogen product in the global menopausal hot flashes market in 2014. Apart from its usage as a sole therapy, estrogen is also used in combination drugs along with progesterone. Duavee and Prempro were the largest types of combination therapeutics sold in the menopausal hot flashes market in 2014.

However, the conventionally approved usage of hormone therapy has come under the spotlight after recent studies showed its association with higher occurrence of cancer, stroke, and blood pressure disorders in women suffering from menopausal hot flashes. As a result, non-hormonal treatment of menopausal hot flashes is rising in demand. The latter comprises of vitamin E supplements and antidepressants. Currently, Brisdelle is the only antidepressant cleared for usage against menopausal hot flashes.

North America Menopausal Hot Flashes Market Leads Global Market

Among the regional segments of the global menopausal hot flashes market, North America emerged as the leader in 2014, due to easier availability of advanced treatments and higher awareness regarding feminine health. Europe is the second largest regional market for menopausal hot flash therapeutics, led by Western European countries such as France, Germany, and the U.K. Steadily increasing availability of feminine health products in Asia Pacific, allied to an increase in awareness about the same and reduction in the social stigma attached to the issue of feminine health, is expected to fuel the Asia Pacific menopausal hot flashes market in the forecast period.

Competitively, the global menopausal hot flashes market is relatively fragmented, due to the entry and promising performance of several small and midsized players. Major players in the menopausal hot flashes market, 44% of which is held by the top ten players, include Bayer AG, Merck & Co. Inc., Pfizer Inc., Novo Nordisk Corporation, and Novartis International AG.

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