Global Research Report explore the PharmaPoint Migraine – Drug Forecast and Market Analysis to 2023


“The Report PharmaPoint: Migraine – Global Drug Forecast and Market Analysis to 2023 provides information on pricing, market analysis, shares, forecast, and company profiles for key industry participants. –

The migraine market is saturated with generic drugs, and the remaining branded products already on the market are expected to lose exclusivity during the next few years, with the exception of Botox for chronic migraine, which is expected to maintain its leading position in terms of sales. However, reformulations of mature products as well as new classes of therapies are anticipated to launch during the forecast period and these will contribute to the market growth. By 2023, the migraine market will grow to $3.7 billion at a compound annual growth rate (CAGR) of 3.6%, with the US continuing to dominate the market as a result of higher drug prices and a large migraine population. Some of the new treatments are expected to target the key unmet needs but opportunities will remain for further treatment choices especially drugs that will offer an improved safety and side-effects profile.

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Key Questions Answered

  • The migraine market is marked by the presence of a number of unmet needs in current treatments. What are the main unmet needs in this market? Will the drugs under development fulfil the unmet needs of the migraine market?

  • The late-stage migraine pipeline is filled with therapies with diverse formulations and routes of administration. Which drug will have a significant impact on the migraine market. Which of these drugs will have the highest CAGR, and why?

  • The migraine market is currently dominated by generic drugs. How will the introduction of combinations of device and drugs, and new classes of therapies change the treatment landscape once reimbursement is not a problem anymore? How will the drug treatment rates change over the next ten years? What are the key drivers and barriers to this change?

Key Findings

  • The main driver of the expansion of the migraine market will be the continuous use of Botox for chronic migraine. The introduction of reformulations of mature products as well as new classes of therapies will further increase the market size.

  • The biggest barrier for the introduction of new therapies will be patent expirations of the majority of the drugs marketed for migraine, which have resulted in an increase of generics, and which may negatively impact revenue from branded drugs that are expected to launch in the forecast period.

  • The concerns of reducing healthcare costs as part of government austerity measures, particularly in Europe, which will impede market growth. To ensure reimbursement companies will have to work closely together with payers and price their drugs competitively.

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  • Overview of migraine, including epidemiology, etiology, pathophysiology, symptoms, diagnosis, and treatment guidelines.

  • Annualized migraine therapeutics market revenue, annual cost of therapy and treatment usage pattern data from 2012 and forecast for ten years to 2023.

  • Key topics covered include market characterization, unmet needs, R&D and clinical trials assessment, late stage clinical trial analysis and implications for the migraine therapeutics market.

  • Pipeline analysis: focus on the seven late-stage pipeline drugs discussing emerging trends as well as overview of earlier phase drugs.

  • Analysis of the current and future market competition in the global migraine therapeutics market. Insightful review of the key industry drivers, restraints and challenges. Each trend is independently researched to provide qualitative analysis of its implications.

Reasons to buy

  • Develop and design your in-licensing and out-licensing strategies through a review of pipeline products and technologies, and by identifying the companies with the most robust pipeline. Additionally a list of acquisition targets included in the pipeline product company list.

  • Develop business strategies by understanding the trends shaping and driving the global migraine therapeutics market.

  • Drive revenues by understanding the key trends, innovative products and technologies, market segments, and companies likely to impact the global migraine therapeutics market in future.

  • Formulate effective sales and marketing strategies by understanding the competitive landscape and by analysing the performance of various competitors.

  • Identify emerging players with potentially strong product portfolios and create effective counter-strategies to gain a competitive advantage.

  • Track drug sales in the global migraine therapeutics market from 2012-2017.

  • Organize your sales and marketing efforts by identifying the market categories and segments that present maximum opportunities for consolidations, investments and strategic partnerships.

Table of Contents

1.1 List of Tables 17

1.2 List of Figures 23

2 Introduction 24

2.1 Catalyst 24

2.2 Related Reports 24

2.3 Upcoming Related Reports 24

3 Disease Overview 25

3.1 Etiology and Pathophysiology 27

3.1.1 Etiology 27

3.1.2 Pathophysiology 28

3.1.3 Prognosis 29

3.2 Symptoms 29

3.2.1 Premonitory Phase 30

3.2.2 Aura Phase 30

3.2.3 Headache Phase 31

3.2.4 Postdrome Phase 31

4 Epidemiology 32

4.1 Disease Background 32

4.2 Risk Factors and Comorbidities 33

4.2.1 Female *** and family history are interrelated risk factors of migraine 33

4.2.2 People with migraine also suffer from several comorbidities 34

4.3 Global Trends 35

4.3.1 US 36

4.3.2 5EU 37

4.3.3 Japan 38

4.4 Forecast methodology 39

4.4.1 Sources used 41

4.4.2 Sources not used 44

4.4.3 Forecast assumptions and methods 44

4.5 Epidemiological Forecast for Migraine (2013-2023) 49

4.5.1 Total Prevalent Cases of Migraine 49

4.5.2 Age-Specific Total Prevalent Cases of Migraine 50

4.5.3 ***-Specific Total Prevalent Cases of Migraine 52

4.5.4 Age-Standardized Total Prevalence of Migraine 54

4.5.5 Total Prevalent Cases of Migraine with Aura and Migraine without Aura 55

4.6 Discussion 57

4.6.1 Conclusions on Epidemiological Trends 57

4.6.2 Limitations of the Analysis 58

4.6.3 Strengths of the Analysis 59

5 Disease Management 60

5.1 Treatment Overview 60

5.1.1 Acute Migraine Treatment 63

5.1.2 Preventive Migraine Treatment 64

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