5EU PharmaPoint: HER2-Positive Breast Cancer – Drug Forecast and Market Analysis to 2023


The Report PharmaPoint: HER2-Positive Breast Cancer – 5EU Drug Forecast and Market Analysis to 2023 provides information on pricing, market analysis, shares, forecast, and company profiles for key industry participants. – MarketResearchReports.biz”

HER2-positive breast cancer is the second most common cancer in the world and the most common cancer in women worldwide. This report focuses on the current treatment landscape, unmet needs, current pipeline, and commercial opportunities in the HER2-positive breast cancer market, with coverage of multiple settings of the disease including neoadjuvant, adjuvant, first-, second-, third-, and fourth-line metastatic.

As in the other seven countries covered in this report, Herceptin is the market leader in France, since it was the first HER2-targeting agent to market. Newly-approved drugs tend to gain market access faster in Germany than in the other four EU countries, and this is reflected in the use of Perjeta and Kadcyla in the German HER2-positive breast cancer market. In 2013, Herceptin was the market leader, accounting for 94% of sales in the Italian HER2-positive market. There will be an increase in the breast cancer market size in Spain during the forecast period due to the increased use of HER2-targeted therapies in the neoadjuvant setting, in particular, Perjeta, which is already approved for use in this setting in the US.

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  • An overview of HER2-Positive Breast Cancer, which includes epidemiology, etiology, symptoms, diagnosis, pathology and treatment guidelines.

  • Annualized the 5EU HER2-Positive Breast Cancer market revenue and future forecasts from 2011 to 2013, forecast for 7 years to 2020.

  • Investigation of current and future market competition for HER2-Positive Breast Cancer.

  • Insightful review of the key industry drivers, restraints and challenges as well as predicted impact of key events.

  • Competitor assessment including device approval analysis and device sales forecasts.

  • Marketed and pipeline product profiles covering efficiency, safety, clinical study details, device approvals, product positioning and device sales forecast.

  • Analysis of unmet needs within the market and opportunities for future players.

  • Technology trends evaluation to assess strength of pipeline.

  • An overview of all devices in development including clinical study details, design and material selection considerations, efficacy reports, and device approval timelines.

  • Company profiles including business description, financial overview and SWOT analysis.

  • Coverage of key market players.

  • Strategic assessment of the HER2-Positive Breast Cancer sector through market impact analysis, future market scenario and company analysis.

  • Direct quotes from Key Opinion Leaders (KOL) as well as doctors

Reasons To Buy

  • Understand the trends shaping and driving the 5EU HER2-Positive Breast Cancer market.

  • Realize device preferences of physicians who have performed the tests already.

  • Access market sizing, forecasts and quantified growth opportunities in the 5EU HER2-Positive Breast Cancer market through 2018.

  • Quantify candidate patient populations to better design product pricing & launch plans.

  • Drive revenues, formulate effective sales and marketing strategies and gain in-depth understanding of the competitive landscape.

  • Perform benchmarking analysis of growth opportunities against currently marketed products.

  • Assess competitiveness of products in market by understanding the strengths and weaknesses of current competition.

  • Take a comprehensive look at the market’s device pipeline and identify promising, paradigm-shifting products.

  • Create an effective counter-strategy to gain a competitive advantage against those currently in the market.

  • Organize your sales and marketing efforts by identifying the market categories and segments that present the best opportunities for growth.

  • What’s the next big thing in the 5EU HER2-Positive Breast Cancer market landscape? Identify, understand and capitalize.

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Table of Contents

1 Table of Contents 6

1.1 List of Tables 10

1.2 List of Figures 14

2 Introduction 15

2.1 Catalyst 15

2.2 Related Reports 16

2.3 Upcoming Related Reports 17

3 Disease Overview 18

3.1 Etiology and Pathophysiology 18

3.1.1 Etiology 18

3.1.2 Pathophysiology 18

3.2 Basic Breast Anatomy 20

3.3 Breast Cancer Staging 21

3.4 Prognosis 22

3.5 Quality of Life 23

3.6 Symptoms 25

4 Disease Management 26

4.1 Treatment Overview 26

4.1.1 Treatment of Early-Stage Breast Cancer (Stage 0 to Stage IB) 26

4.1.2 Treatment of Locally-Advanced and Regional Breast Cancer (Stage IB to IIIA) 27

4.1.3 Treatment of Metastatic HER2-Positive Breast Cancer (Stage IV) 30

4.2 France 32

4.2.1 Diagnosis 32

4.2.2 Clinical Practice 33

4.3 Germany 35

4.3.1 Diagnosis 35

4.3.2 Clinical Practice 36

4.4 Italy 38

4.4.1 Diagnosis 38

4.4.2 Clinical Practice 38

4.5 Spain 41

4.5.1 Diagnosis 41

4.5.2 Clinical Practice 42

4.6 UK 43

4.6.1 Diagnosis 43

4.6.2 Clinical Practice 44

5 Competitive Assessment 47

5.1 Overview 47

5.2 Product Profiles – HER2-Targeted Therapies 48

5.2.1 Herceptin (trastuzumab) 48

5.2.2 Tykerb (lapatinib) 54

5.2.3 Perjeta (pertuzumab) 59

5.2.4 Kadcyla (ado-trastuzumab emtansine, T-DM1) 63

5.3 Product Profiles – General Targeted Therapies 67

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