Global PharmaPoint Dry Eye Syndrome – Drug Forecast and Market Assessment to 2024

“The Report PharmaPoint: Dry Eye Syndrome – Global Drug Forecast and Market Assessment to 2024 provides information on pricing, market analysis, shares, forecast, and company profiles for key industry participants. –


Dry Eye Syndrome (DES), also known as keratoconjunctivitis sicca, is a multifactorial disease of the tears and ocular surface. This ocular condition can cause ocular discomfort, visual disturbances, and tear film instability, which can potentially damage the ocular surface. The DES market has had few new therapeutics in the last decade with Japan seeing the most change in this time with the arrival of Diquas and Mucosta in 2010 and 2013, respectively. However, the lack of treatment options is about to change with the expected launch of numerous pipeline DES drugs during the forecast period, which will be a significant driver of growth in the 9MM. Indeed, this change has already been initiated with Ikervis’ recent arrival in Europe in 2015. Furthermore, additional marketing approvals are being sought for currently marketed DES drugs, Restasis and Diquas, in new countries in the 9MM, which will provide a source of growth in this market.

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Key Questions Answered

  • The DES market has been dominated by artificial tears therapy and by Restasis (in the US) for many years, with little approved therapeutic options available in the 9MM. New classes of drugs are anticipated the reach the market within the forecast period. How will these change the market overall during the forecast period? Will Restasis maintain market dominance in 2024?

  • The current late stage DES pipeline is varied, with first-in-class drugs in development with innovative modes of action. Which of these will have the biggest impact on the market? What strategies are developers undertaking to penetrate this chronically underserved market? Will these fulfil any unmet needs?

  • Population aging is occurring in almost all countries worldwide, particularly in the 9MM. This is expected to have a significant impact on the prevalence of age-related diseases such as DES. How will epidemiological changes impact the growth of the future market?

Key Benefits

  • The main driver of growth in the DES market will be the introduction of first-in-class drugs over the forecast period. The launch of these therapies will act as a stimulant for growth in this chronically underserved market.

  • DES has been a high risk indication for developers, with numerous drugs failing in late stage development. This has acted as a significant barrier to growth in this market historically.

  • The arrival of new therapies across the 9MM will increase treatment rates and provide alternative options for many patients.

  • The largest unmet need in the DES market will remain the lack of additional safe and efficacious therapeutics with novel modes of action. In addition, simplifying dosing regimens is an important consideration for companies developing drugs to treat these patients.

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Overview of DES, including epidemiology, etiology, pathophysiology, symptoms, diagnosis, and treatment guidelines.

Annualized DES market revenue, annual cost of therapy and treatment usage pattern data from 2014 and forecast for ten years to 2024.

Key topics covered include market characterization, unmet needs, R&D and clinical trials assessment, late stage clinical trial analysis and implications for the glaucoma therapeutics market.

Pipeline analysis: focus on the four late-stage pipeline DES drugs discussing emerging trends as well as overview of earlier phase drugs.

Analysis of the current and future market competition in the global DES therapeutics market. Insightful review of the key industry drivers, restraints and challenges. Each trend is independently researched to provide qualitative analysis of its implications.

Reasons to buy

The report will enable you to –

Develop and design your in-licensing and out-licensing strategies through a review of pipeline products and technologies, and by identifying the companies with the most robust pipeline. Additionally a list of acquisition targets included in the pipeline product company list.

Develop business strategies by understanding the trends shaping and driving the global glaucoma therapeutics market.

Drive revenues by understanding the key trends, innovative products and technologies, market segments, and companies likely to impact the global DES therapeutics market in future.

Formulate effective sales and marketing strategies by understanding the competitive landscape and by analysing the performance of various competitors.

Identify emerging players with potentially strong product portfolios and create effective counter-strategies to gain a competitive advantage.

Track drug sales in the global DES therapeutics market from 2014-2024.

Organize your sales and marketing efforts by identifying the market categories and segments that present maximum opportunities for consolidations, investments and strategic partnerships.

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Table Of Content

Table of Contents

1 Table of Contents 8

1.1 List of Tables 14

1.2 List of Figures 17

2 Introduction 19

2.1 Related Reports 19

3 Disease Overview 21

3.1 Etiology and Pathophysiology 21

3.1.1 Etiology 21

3.1.2 Pathophysiology 24

3.2 Disease Classification 26

3.3 Symptoms 27

3.4 Prognosis 30

3.5 Quality of Life 31

4 Epidemiology 32

4.1 Risk Factors and Comorbidities 32

4.1.1 Risk of Dry Eye Syndrome Increases 35% Each Decade after Age 40 33

4.1.2 Women are twice as likely to have Dry Eye Syndrome as men 33

4.1.3 Use of certain medications may increase the risk of developing Dry Eye Syndrome 34

4.1.4 Diets rich in Omega-3 fatty acid may prevent dry eye syndrome 35

4.1.5 Certain environmental conditions can double the risk of Dry Eye Syndrome 35

4.2 Global Trends 36

4.2.1 US 36

4.2.2 5EU 36

4.2.3 Asia 37

4.3 Forecast Methodology 38

4.3.1 Sources used 39

4.3.2 Forecast Assumptions and Methods -Total Prevalent Cases of Dry Eye Syndrome 41

4.3.3 Sources Not Used 44

4.4 Epidemiology Forecast for Dry Eye Syndrome (2014-2024) 44

4.4.1 Total Prevalent Cases of Dry Eye Syndrome 44

4.4.2 Age-Specific Total Prevalent Cases 46

4.4.3 ***-Specific Total Prevalent Cases 48

4.4.4 Age-Standardized Total Prevalence of Dry Eye Syndrome 50

4.4.5 Total Prevalent Cases of Dry Eye Syndrome by Severity 51

4.5 Discussion 52

4.5.1 Conclusions on Epidemiology Trends 52

4.5.2 Limitations of Analysis 53

4.5.3 Strengths of Analysis 54

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